This is a bilingual snapshot page saved by the user at 2025-7-16 21:32 for https://app.immersivetranslate.com/word/, provided with bilingual support by Immersive Translate. Learn how to save?

1、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Epidemiology, clinical presentation, and outcome of mpox: A study of 381 cases in Saudi Arabia

作者(们): Abdullah M Assiri 1, Haleema Alserehi 1, Musallam Yunus Abuhasan 1, Einas Adul Aziz Khalil 1, Mohammed Hussain Al-Thunayan 1, Mohammed Saaban Alshehri 1, Amirah Abdulmohsen Alrossais 1, Abdulrahman Saeed Abudahish 1, Abdullah Jaber Alsahafi 1, Jaffar A Al-Tawfiq 2 3 4

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

160

Case series (single-arm uncontrolled study)

Not serious

Not serious

Not serious

Serious A

47

160

Incident rate
0.29 each (0.22 to 0.37)

⨁⨁⨁◯
Moderatea

2、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: A plague passing over: Clinical features of the 2022 mpox outbreak in patients of color living with HIV

作者(们): Zoha K Momin 1, Aleuna Lee 1, Travis W Vandergriff 1,2, Jason E Bowling 3, Bahir Chamseddin 1, Arturo Dominguez 1,4, Gregory A Hosler 1,2,5, Richard C Wang 1,*, Ellen Kitchell 4,* Zoha K Momin 1、 Aleuna Lee 1、 Travis W Vandergriff 1、2、 Jason E Bowling 3、 Bahir Chamseddin 1、 Arturo Dominguez 1、4、 Gregory A Hosler 1、2、5、 Richard C Wang 1、*、 Ellen Kitchell 4、*

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

36

Case series (single-arm uncontrolled study)

Not serious

Not seriousA

Not seriousA

Not serious

10

36

Incident rate
0.28 each (0.14 to 0.45)

⨁⨁⨁⨁
Higha

问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Demographic, clinical and microbiological characteristics of the first 30 human monkeypox confirmed cases attended in a tertiary hospital in Madrid (Spain), during the May-June 2022 international outbreak

作者(们): Alejandro Cobos 1、 Maricela Valerio 1、2、3、4、1、2、 María Palomo 1、 Iván Adán 1、2、 Pilar Catalán 1、2、 Cristina Veintimilla 1、 Felipe López-Andújar 1、 Cristina Rincón 1、 Alicia Galar 1、2、 Roberto Al. onso 1、2、3、4、 Marina Machado 1、2、 Paloma Gijón 1、2、 Teresa Aldámiz-Echevarría Lois 1、2、5、 Leire Pérez Latorre 1、2、5、 Cristina Diez 1、2、5、 Chiara Fanciulli 1、2、5、 Emilio Bouza Santiago 1、2、3、4、 Patricia Muñoz 1、2、3、4

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

30

Case series (single-arm uncontrolled study)

Not serious

severe

Not serious

Not serious

18

30

Incident rate
0.6% (0.41 to 0.77)

⨁⨁⨁◯
Moderatea

Explanations

(28/30) Routine PCR diagnosis received by patients, (2/30) Blood PCR testing received by patients

4、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Human Monkeypox Experience in a Tertiary Level Hospital in Milan, Italy, between May and October 2022: Epidemiological Features and Clinical Characteristics

作者(们): Caterina Candela 1,*, Angelo Roberto Raccagni 1, Elena Bruzzesi 1, Costanza Bertoni 1, Alberto Rizzo 2, Gloria Gagliardi 2, Diana Canetti 3, Nicola Gianotti 3, Davide Mileto 2, Maria Rita Gismondo 2, Antonella Castagna 1,3, Silvia Nozza, on behalf of Centro San Luigi (CSL) Working Group1,3

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

140

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

severe

71

140

Incident rate
0.5% (0.42 to 0.59)

⨁⨁◯◯

5、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection: an observational cohort study

作者(们): Morgane Mailhe 1,†, Anne-Lise Beaumont 1,∗,†, Michael Thy 1, Diane Le Pluart 1, Ségolène Perrineau 1, Nadhira Houhou-Fidouh 2, Laurène Deconinck 1, Chloé Bertin 1, Valentine Marie Ferré 2, Marie Cortier 1, Clémentine De La Porte Des Vaux 1, Bao-Chau Phung 1, Bastien Mollo 1, Mélanie Cresta 1, Fabrice Bouscarat 3, Christophe Choquet 4, Diane Descamps 2,5, Jade Ghosn 1,5, François-Xavier Lescure 1,5, Yazdan Yazdanpanah 1,5, Véronique Joly 1,5, Nathan Peiffer-Smadja 1,5

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

264

Case series (single-arm uncontrolled study)

Not serious

Not serious

Very serious

severe

82

264

Incident rate
0.3% (0.26 to 0.37)

⨁◯◯◯
Very low

Explanations

(209/264) Patient has a history of sexually transmitted diseases, and (5/264) Patient has a history of cancer

6、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Demographic and clinical characteristics of confirmed human monkeypox virus cases in individuals attending a sexual health centre in London, UK: an observational analysis

作者(们): Nicolò Girometti a,*, Ruth Byrne a, Margherita Bracchi a, Joseph Heskin a, Alan McOwan a, Victoria Tittle a, Keerti Gedela a, Christopher Scott a, Sheel Patel a, Jesal Gohil a, Diarmuid Nugent a, Tara Suchak a, Molly Dickinson a, Margaret Feeney a, Borja Mora-Peris a,b, Katrina Stegmann a,c, Komal Plaha a,c, Gary Davies a, Luke S P Moore a,b,d, Nabeela Mughal a,b,d, David Asboe a, Marta Boffito a,d, Rachael Jones a, Gary Whitlock a

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

54

Case series (single-arm uncontrolled study)

Not serious

Not serious

Very serious

severe

15

54

Incident rate
0.3% (0.16 to 0.42)

⨁◯◯◯
Very low

7、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study

作者(们): Eloy José Tarín-Vicente 1, Andrea Alemany 2, Manuel Agud-Dios 1, Maria Ubals 2, Clara Suñer 2, Andrés Antón 3, Maider Arando 4, Jorge Arroyo-Andrés 1, Lorena Calderón-Lozano 1, Cristina Casañ 5, José Miguel Cabrera 6, Pep Coll 6, Vicente Descalzo 4, María Dolores Folgueira 7, Jorge N García-Pérez 4, Elena Gil-Cruz 1, Borja González-Rodríguez 1, Christian Gutiérrez-Collar 1, Águeda Hernández-Rodríguez 8, Paula López-Roa 9, María de Los Ángeles Meléndez 9, Julia Montero-Menárguez 1, Irene Muñoz-Gallego 9, Sara Isabel Palencia-Pérez 10, Roger Paredes 11, Alfredo Pérez-Rivilla 7, María Piñana 3, Nuria Prat 12, Aída Ramirez 5, Ángel Rivero 6, Carmen Alejandra Rubio-Muñiz 1, Martí Vall 2, Kevin Stephen Acosta-Velásquez 13, An Wang 1, Cristina Galván-Casas 14, Michael Marks 15, Pablo L Ortiz-Romero 10, Oriol Mitjà 16

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

181

Case series (single-arm uncontrolled study)

Not serious

Not serious

Very serious

severe

181

181

Incident rate
1.0% (0.98 to 1)

⨁◯◯◯
Very low

8、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Clinical Features of Mpox Patients in Korea: A Multicenter Retrospective Study

作者(们): So Yun Lim # 1, Hyeon Jae Jo # 2, Su-Yeon Lee 3, Miyoung Ahn 4, Yeonjae Kim 1, Jaehyun Jeon 1, Eu Suk Kim 2 5, BumSik Chin 6, Jae-Phil Choi 7, Nam Joong Kim 8

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

60

Case series (single-arm uncontrolled study)

Not serious

Not serious

Very serious

Not serious

35

60

Incident rate
0.6% (0.45 to 0.71)

⨁⨁◯◯

9、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Diagnostic Value of SAA Levels and Perianal Symptoms in the Complicated Perianal Abscesses Among Mpox-Infected Patients

作者(们): Yi Wang 1,2, Wenhui Zhang 1,3, Shourong Liu 1, Fei Wang 1, Qian Huang 1, Er Li 3, Mingli Zhu 4, Jianhua Yu 1,*,✉, Jinchuan Shi 1,*

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

48

Case series (single-arm uncontrolled study)

Very serious

Not serious

Not seriousA

Not serious

2

48

Incident rate
0.0% (0.01 to 0.14)

⨁⨁◯◯
Low a

Explanations

a. 5 mpox-infected patients were excluded due to tonsillitis or sepsis, and one was excluded due to death.

10、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Observational Cohort Study of Evolving Epidemiologic, Clinical, and Virologic Features of Monkeypox in Southern France

作者(们): Nadim Cassir 1,2,3,4,5,✉, Florian Cardona 1,2,3,4,5, Hervé Tissot-Dupont 1,2,3,4,5, Christiane Bruel 1,2,3,4,5, Barbara Doudier 1,2,3,4,5, Salima Lahouel 1,2,3,4,5, Karim Bendamardji 1,2,3,4,5, Céline Boschi 1,2,3,4,5, Sarah Aherfi 1,2,3,4,5, Sophie Edouard 1,2,3,4,5, Jean-Christophe Lagier 1,2,3,4,5, Philippe Colson 1,2,3,4,5, Philippe Gautret 1,2,3,4,5, Pierre-Edouard Fournier 1,2,3,4,5, Philippe Parola 1,2,3,4,5, Philippe Brouqui 1,2,3,4,5, Bernard La-Scola 1,2,3,4,5, Matthieu Million 1,2,3, 4,5

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms (随访: 平均值 3 月)

136

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

85

136

Incident rate
0.6% (0.54 to 0.71)

⨁⨁⨁◯
Moderatea

11、

问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

Reference: Clinical characteristics of monkeypox complicated with human immunodeficiency virus infection/acquired immunodeficiency syndrome in Chengdu

Authors(s): Luo Haixia1, Mao Yi1, Bao Lei2, Wu Guihui3, Cheng Yao

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms (follow-up: mean 40 days)

56

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

27

56

Incident rate
0.5% (0.35 to 0.62)

⨁⨁⨁◯
Moderatea

12、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Clinical characteristics of human monkeypox, and risk factors for severe disease

作者(们): Gregory D Huhn 1, Audrey M Bauer, Krista Yorita, Mary Beth Graham, James Sejvar, Anna Likos, Inger K Damon, Mary G Reynolds, Matthew J Kuehnert

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

34

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

30

34

Incident rate
0.9% (0.73 to 0.97)

⨁⨁⨁◯
Moderatea

13、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Clinical Course and Outcome of Human Monkeypox in Nigeria

作者(们): Dimie Ogoina , Michael Iroezindu , Hendris Izibewule James , Regina Oladokun , Adesola Yinka-Ogunleye , Paul Wakama , Bolaji Otike-odibi , Liman Muhammed Usman , Emmanuel Obazee , Olusola Aruna , Chikwe Ihekweazu

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms (随访: 平均值 3 月)

31

Case series (single-arm uncontrolled study)

Very serious

Not serious

Serious A

Not serious

31

40

Incident rate
0.8% (0.62 to 0.89)

⨁◯◯◯
Very lowa

Explanations

a. Five of the 40 (12.5%) cases died: (1) a 34-year-old man who died by suicide (background psychiatry illness could not be established)

14、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Update: Multistate Outbreak of Monkeypox --- Illinois, Indiana, Kansas, Missouri, Ohio, and Wisconsin, 2003

作者(们): Dimie Ogoina , Michael Iroezindu , Hendris Izibewule James , Regina Oladokun , Adesola Yinka-Ogunleye , Paul Wakama , Bolaji Otike-odibi , Liman Muhammed Usman , Emmanuel Obazee , Olusola Aruna , Chikwe Ihekweazu

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

16

Case series (single-arm uncontrolled study)

Not serious

Not serious

Not serious

severe

16

87

Incident rate
0.2% (0.11 to 0.28)

⨁⨁⨁◯
Moderatea

15、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Mpox in the Emergency Department: A Case Series

作者(们): Michael Musharbash 1, Madeline DiLorenzo 2, Nicholas Genes 1, Vikramjit Mukherjee 2, Amanda Klinger 2

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms (随访: 平均值 3 月)

22

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

severe

22

79

Incident rate
0.3% (0.18 to 0.39)

⨁⨁◯◯
Low a

16、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Monkeypox Outbreak 2022: Clinical and Virological Features of 30 Patients at the Sexually Transmitted Diseases Centre of Sant’ Orsola Hospital, Bologna, Northeastern Italy

作者(们): Valeria Gaspari a,#, Giada Rossini b,#, Silvia Robuffo a,c, Luca Rapparini a,c,✉, Alessandra Scagliarini c, Alessandra Mistral De Pascali c, Bianca Maria Piraccini a,c, Tiziana Lazzarotto b,c

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms (follow-up: mean 5 days)

30

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

severe

10

30

Incident rate
0.3% (0.17 to 0.53)

⨁⨁◯◯
Low a

17、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Monkeypox outbreak in Madrid (Spain): Clinical and virological aspects

作者(们): Eva Orviz a,1, Anabel Negredo b,1, Oskar Ayerdi a, Ana Vázquez b, Ana Muñoz-Gomez a, Sara Monzón c, Petunia Clavo a, Angel Zaballos d, Mar Vera a, Patricia Sánchez b, Noemi Cabello e, Pilar Jiménez d, Jorge A Pérez-García a, Sarai Varona c, Jorge del Romero a, Isabel Cuesta c, Alberto Delgado-Iribarren a, Montse Torres f, Iñigo Sagastagoitia e, Gustavo Palacios g, Vicente Estrada e,⁎, Maria Paz Sánchez-Seco b; , On behalf of Grupo Viruela del Simio Madrid CNM/ISCIII/HCSC/Sandoval2

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

48

Case series (single-arm uncontrolled study)

Not serious

Not serious

Not serious

Not serious

21

48

Incident rate
0.4% (0.29 to 0.59)

⨁⨁⨁⨁
Higha

18、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series

作者(们): Aatish Patel 1,✉, Julia Bilinska 1, Jerry C H Tam 1, Dayana Da Silva Fontoura 1, Claire Y Mason 1, Anna Daunt 1, Luke B Snell 1, Jamie Murphy 1, Jack Potter 1, Cecilia Tuudah 1, Rohan Sundramoorthi 1, Movin Abeywickrema 1, Caitlin Pley 1, Vasanth Naidu 1, Gaia Nebbia 1, Emma Aarons 1, Alina Botgros 1, Sam T Douthwaite 1, Claire van Nispen tot Pannerden 1, Helen Winslow 1, Aisling Brown 1, Daniella Chilton 1, Achyuta Nori 1

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

197

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

60

197

Incident rate
0.3% (0.24 to 0.37)

⨁⨁⨁◯
Moderatea

19、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Viral loads in clinical samples of men with monkeypox virus infection: a French case series

作者(们): Romain Palich a,*, Sonia Burrel b, Gentiane Monsel a, Agathe Nouchi a, Alexandre Bleibtreu c, Sophie Seang a, Vincent Bérot a, Cécile Brin a, Ariane Gavaud a, Yara Wakim a, Nagisa Godefroy a, Antoine Fayçal a, Yanis Tamzali a, Thomas Grunemwald d, Michel Ohayon d, Eve Todesco b, Valentin Leducq b, Stéphane Marot b, Vincent Calvez b, Anne-Geneviève Marcelin b, Valérie Pourcher a

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

50

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

11

50

Incident rate
0.2% (0.12 to 0.36)

⨁⨁⨁◯
Moderatea

20、curse of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Epidemiologic Characteristics of Mpox among People Experiencing Homelessness, Los Angeles County, California, USA, 2022

作者(们): Hannah K Brosnan 1, Karen W Yeh 1, Padma S Jones 1, Sohum Gokhale 1, Dalia Regos-Stewart 1, Hang Tran 1, Kathleen Poortinga 1, Phoebe Danza 1, Rebecca Fisher 1, Lauren E Finn 1, Chelsea Foo 1, Alicia H Chang 1,✉

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

39

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

39

118

Incident rate
0.3% (0.25 to 0.42)

⨁⨁⨁◯
Moderatea

21、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: [Twelve cases of monkeypox virus outbreak in Bangassou District (Central African Republic) in December 2015]

作者(们): E. Kalthan · J.P. Dondo-Fongbia · S. Yambele · L.R. Dieu-Creer · R. Zepio · C.M. Pamatika

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

12

Case series (single-arm uncontrolled study)

Not serious

Not serious

Not serious

Very serious

4

12

Incident rate
0.3% (0.1 to 0.65)

⨁⨁◯◯
Low a

22、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Association of Tecovirimat Therapy With Mpox Symptom Improvement: A Cross-sectional Study-King County, Washington, May-October 2022

作者(们): Ellora N Karmarkar 1,✉, Matthew R Golden 2,3, Roxanne P Kerani 4,5, Sargis Pogosjans 6, Eric J Chow 7,8,9, Rachel A Bender Ignacio 10,11, Meena S Ramchandani 12,13, Meagan K Kay 14, Chase A Cannon 15,16, Julia C Dombrowski 17,18,✉,2

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms (随访: 平均值 5 月)

115

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

44

115

Incident rate
0.4% (0.29 to 0.48)

⨁⨁⨁◯
Moderatea

23、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

参考资料: Epidemiological characteristics, clinical manifestations, and mental health status of human mpox cases: A multicenter cross‐sectional study in China

作者(们): Leiwen Fu1 | Bingyi Wang 1 | Ke Wu 2 | Liuqing Yang 3 | Zhongsi Hong 4 | Ziyu Wang 5 | Xiaojun Meng6 | Ping Ma5 | Xiao Qi 2 | Guangyong Xu7 | Fuxiang Wang 3 | Weijie Zhang 1 | Chenming Huang 2 | Dingyan Zhang 2 | Yuanlong Lin3 | Wanxian Cao 8 | Ping Sun4 | Weibo Wu 3 | Yong Gao 8 | Fan Lv 9 | Jun Qian1 | Hongzhou Lu3 | Huachun Zou 10,11,12

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

115

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

19

115

Incident rate
0.2% (0.1 to 0.25)

⨁⨁⨁◯
Moderatea

24、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

Reference: Comparison of the clinical features of monkeypox in HIV infection and non-infected individuals

Authors: Yan Jun, Zhang Zhongdong, Yan Dingyan, Li Feng, Zheng Rongrong, Shi Jinchuan, Liu Shourong, Yu Jianhua

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

31

Case series (single-arm uncontrolled study)

Not serious

Not serious

Serious A

Not serious

5

31

Incident rate
0.2% (0.5 to 0.34)

⨁⨁⨁◯
Moderatea

25、问题: Course of [mpox] over [respiratory symptoms]

环境: Symptoms of patients infected with MPOX

Reference: Analysis of the clinical characteristics of 38 patients with monkeypox in Hangzhou

Authors: Xu Jingying, Huang Qian, Yu Jianhua, Wang Fei, Xiao Cunshu, Xun Jing, Meng Ziqiang, Zhang Tianbin, Liu Shourong

№; Researched

Certainty assessment

effect

Certainty

importance

Study design

Risk of bias

Inconsistency

Indirectness

accuracy

Other Considerations [Notes]

№ of events

№ of individuals

Rate
(95% CI)

respiratory symptoms

38

Case series (single-arm uncontrolled study)

Not serious

Not serious

severe

Not serious

8

38

Incident rate
0.2% (0.1 to 0.37)

⨁⨁⨁◯
Moderatea