Granular cell tumor:　　Malignant granular cell tumor is rare, often occurs in the skin or subcutaneous tissue, and a few are also seen in the bladder and larynx. It usually occurs in adults, with a male to female ratio of 1:3. There are two types, one is clinically malignant and histologically benign; the other is clinically and histologically malignant. Ulcers often occur. The most recognized malignant criteria are: 1. Benign pathological morphology, but clinical recurrence or metastasis; 2. Volume greater than 4-5cm, nuclear division 2/10HPF, spindle cell tumor, large nucleus with obvious nucleolus, necrosis, rapid growth or recurrence. These six phenomena do not have to be all present.